Job Description

Location : Cambridge, MA (Onsite)

Job Overview: Our client is seeking an experienced and strategic Director of Chemistry to be a leader in our chemistry function, driving the design, synthesis, and optimization of novel compounds across our drug discovery pipeline with a focus on Computational techniques.

Primary Job Responsibilities:

• Oversee hit-to-lead and lead optimization efforts using SAR, structure-based design, and ADME/PK data
• Collaborate with cross-functional partners (biology, pharmacology, DMPK, CMC) to define project strategy and ensure timely progression
• Drive in-silico screening and use of relevant computational chemistry techniques
• Manage CRO relationships for synthesis, purification, and analytical support
• Contribute to compound IP strategy and coordinate with legal on patent filings

Primary Job Requirements:

• Ph.D. in Medicinal Chemistry, Organic Chemistry, or a related field; exceptional candidates with an M.Sc. and significant industry experience will also be considered.
• Proven track record in advancing small molecules from discovery through preclinical stages
• Strong expertise in medicinal chemistry, SAR development, and lead optimization
• Experience in in-silico screening, high-throughput screening, and DEL

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

PROVEN SCIENTIFIC PLACEMENT

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

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