ROLE SUMMARY
The ADC (Antibody Drug Conjugate) Chemistry group is seeking a highly motivated, creative, and experienced computational chemist with a proven track record of success in drug discovery, to develop novel payloads and linkers for antibody-drug conjugates (ADCs).
You will apply your background in drug development, medicinal chemistry, and computational chemistry to develop new anticancer therapies. Your background in structure-based drug discovery is critical for this position. You will work collaboratively within the chemistry department and researchers across the biology and translational sciences. You will play a vital role as scientific leader and key contributor to large, multi-disciplinary, matrix teams from project inception to delivery of clinical drug candidates.
The successful candidate will be responsible for identifying key opportunities for computational chemistry to impact drug discovery at all stages ranging from target evaluation to hit identification to lead optimization and candidate selection. You will also utilize your computational chemistry and scientific programming expertise to identify methods that can address key challenges and impact drug discovery across the portfolio.
The candidate should have good communication and organizational skills and have the ability to work in a flexible, dynamic team environment. As an independent researcher and leading member of project teams in Oncology, you will have opportunities to make numerous direct contributions to Pfizer's drug discovery efforts.
ROLE RESPONSIBILITIES:
You will:
BASIC QUALIFICATIONS:
PREFERRED QUALIFICATIONS:
Preferred candidates will have leading-edge knowledge of the following areas with significant experience with most of them:
ORGANIZATIONAL RELATIONSHIPS
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT
REQUIREMENTS
Occasional travel to Pfizer La Jolla is expected for key interactions with La Jolla Computational Chemistry, Medicinal Chemistry and Structural Biology.
Additional Information:
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